What is Mesothelioma?
There are estimated 2000-3000 new cases of mesothelioma in the
Mesothelioma is a type of cancer involving mesothelial tissues of body organs usually lungs or abdominal. It is often caused by exposure to asbestos. However, there are 30-50% of patients without any history of asbestos exposure. People who have received asbestos exposure of as little as one or two months to very low doses are at risk of mesothelioma cancer. Even people who wash clothes of asbestos exposed people are at risk. A person exposed to asbestos could develop mesothelioma after 50 years of exposure.
People in the occupations such as construction jobs in shipyards, insulators, boilermakers, etc. are at the risk of contracting asbestos disease.
The 2 common types of mesothelioma are:
Pleural mesothelioma (lung cancer) and peritoneal mesothelioma (abdomen organs). The survival time for a patient with diffuse malignant mesothelioma is from
The chance of recovery for a patient with mesothelioma depends on size and location of the cancer, age of the patient and his response to the treatment. Presently, the treatment options for mesotheliomas are:
Imagine a disease that lays eggs inside your lungs. These eggs do not produce discomfort or coughing, they don't cause outbreaks or rashes or anything of the sort. In fact these eggs don't do anything except sit in your lungs and germinate for 30 to 40 years. After this time you begin to have a slight cough, a fever, maybe some cold sweats. You write it off as the flu and continue as usual until it goes away. 3 weeks later the flu is back but this time you're coughing up blood. You visit your doctor and hope he can prescribe something to kick this crazy flu. Your doctor runs a few tests and sends you home. A week later your brought into his office and he lays the devastating news on you...you have Mesothelioma a cancer of the lungs.
This is the reality for roughly 2000 men and women residing here in the
"At 42, I never thought that I would be facing a terminal illness, especially one relating to the lungs. I've never smoked and have leaded a relatively healthy life. I have two beautiful daughters who will be heading to college soon - and I may not be alive to see their graduation."
The primary cause of mesothelioma cancer is linked to exposure to asbestos fibers which are breathed into the lungs or swallowed. Asbestos is a material that was used heavily for many years in hundreds of products. Asbestos was primarily used due to the fact that it is strong, resists fire and corrosion, and has very effective properties for insulation.
In modern day, asbestos has many uses such as thermal pipe and boiler insulation, floor coverings, ceiling tiles, spray-applied fire proofing and sound proofing, roofing materials and "transit" pipe and sheeting. Though major public use was discontinued in the late 70s, asbestos continues to be a material used in countries outside of the
Many more cases of mesothelioma, due to asbestos exposure, are beginning to surface today. First, because our understanding and ability to recognize the disease has increased by leaps and bounds over the years, and second, because this particular cancer lays dormant within the carriers system for 30 to 40 years. With the widespread use of asbestos during the 20th century we are starting to see the consequences of exposure to this toxic material.
Due to the fact that asbestos was in heavy concentration in the industrial and building trades during the mid 1900s, most carriers of mesothelioma cancer are men who where working around asbestos during that time. However, mesothelioma has been reported not only in cases of direct exposure, but also indirect, such as the families of these men, as they often returned home with asbestos fibers on their clothing. Even in today's day and age where asbestos has been all but removed from our lives, it is still possible to be diagnosed with mesothelioma as cases of this cancer have been diagnosed without the presence of asbestos exposure.
At some point during our childhood we have all been told to eat our vegetables. Forcing down tasteless green beans and Brussels sprouts were supposed to make us taller and stronger. Well, so it is for mesothelioma patients. Diet is often an overlooked subject for cancer patients, but eating the right nutritional foods for strength and energy is just as important as taking the proper medication.
Mesothelioma patients undergoing treatment must follow a special cancer diet devised by their nutritionists. Cancer diets involve eating the correct amounts of protein and calories as well as drinking the right amount of water to keep the ailing body replenished and energized. The body needs plenty of nourishment when it is going through chemotherapy or even when the patient is taking certain medications.
Doctors and nutritionists may also recommend a special cancer diet because many mesothelioma patients tend to lose their appetites due to worry over their condition. Also, those who are undergoing treatment may choose not to eat because of the unpleasant side effects they may experience. Chemotherapy, for example, and even some particular medications may cause an imbalance of nutrients that must be corrected in order to keep the body as strong as possible and to keep the patient from losing an excessive amount of weight. Other side effects of mesothelioma treatment include nausea, vomiting, dry mouth, a change in the sense of smell or taste, and/or constipation.
Below are some of the important nutrients patients are encouraged to include in their mesothelioma diet:
Protein is important for any cancer patient because it helps repair tissue damaged by surgery, chemotherapy, or radiation. Protein also helps maintain a strong and healthy immune system, lowering a mesothelioma patient’s risk of infection after aggressive cancer treatments. The National Cancer Institute recommends increasing protein in a cancer diet with cheese, milk, ice cream, yoghurt, eggs, nuts, peanut butter, meats and fish.
Fats are an essential part of the cancer diet because they supply the body with the necessary energy it needs while undergoing treatment. The amount of fats (meaning the number of calories) a cancer diet should consist of is dependent on a mesothelioma patient’s age and body size. The National Cancer Institute recommends increasing caloric intake with such foods as butter, milk, cheese, honey, sugar, granola and dried fruits.
Water is another essential element of the cancer diet. Without a substantial amount of water, the body will dehydrate. It is important that anyone undergoing cancer treatment receive enough water to keep their bodies hydrated and replenished.
The details of every patient’s mesothelioma diet will vary. Some patients will need to incorporate more fat into their diets, while others may need more protein. It is important that patients devise a cancer diet under the guidance of their doctor and nutritionist to ensure that they receive the proper amount of nutrients to improve their quality of life.
a. Active surveillance (or watchful waiting)
Some types of cancer grow very slowly and may cause no problems for many years. In this situation you may not need to have any treatment for some time, but your doctor will monitor you closely so that if the cancer does start to grow you can be given treatment at that time.
b. Surgery
An operation is done to remove the tumour. Surgery is often used if the cancer is only in one area of the body and has not spread. It may be used to remove lymph nodes if these are also affected by the cancer. It can sometimes be used to remove a cancer that has spread to another area of the body, but this is less common. The type of operation will depend on the area of the body affected by the cancer, and on the size and position of the tumour.
c. Radiotherapy
This is the use of high energy x-rays to destroy cancer cells, but cause as little harm as possible to normal cells. The radiotherapy is aimed at the affected area of the body and is very carefully planned. It can cause side effects and the most common is tiredness. The side effects will depend on the part of the body that is being treated.
d. Chemotherapy
Chemotherapy is the use of anti-cancer (cytotoxic) drugs to destroy cancer cells. There are more than 50 different chemotherapy drugs. Some are given as tablets or capsules but most are given by drip (infusion) into a vein. The drugs go into the bloodstream and travel throughout the body to treat the cancer cells wherever they are. Sometimes just one chemotherapy drug is used, but often a combination of two, three or more drugs is given.
Chemotherapy can cause side effects. The side effects will depend on which drug (or combination of drugs) is used. There are now very good ways of preventing or reducing the side effects of chemotherapy.
e. Hormonal therapy
Hormonal therapies work by altering the levels of particular hormones in the body. Some cancers depend on certain hormones in order to divide and grow. By altering the level of hormones in the body, or blocking the hormones from attaching to the cancer cells the cancer can be controlled.
f. Biological therapy
Biological therapies use substances that occur naturally in the body to destroy cancer cells. There are several types of biological therapy, including: monoclonal antibodies, cancer growth inhibitors, vaccines and gene therapy.
Monoclonal antibodies are drugs that can 'recognise' and find specific cells in the body. They can be designed to find a particular type of cancer cell, attach itself to them and destroy them. They can also carry a radioactive molecule, which then delivers radiation directly to the cancer cells.
Cancer growth inhibitors interfere with the way cancer cells use 'chemical messengers' to help the cell to develop and divide. Research is trying to see whether vaccines and gene therapy can be given to treat a cancer that has come back or has spread. Vaccines may also be able to reduce the chance of a cancer coming back, but this type of research is in the very early stages.
There are some common signs and symptoms that may alert you to the fact that something is new or different. You should contact your doctor if you have any of the following:
1. Lumps
Knowing how your body normally looks and feels can help you spot any early changes that could be caused by cancer. You should see your GP if you notice a lump anywhere in your body. It can be useful to tell them how long it’s been there and whether it is getting bigger, or causes discomfort. Cancerous lumps are often (but not always) painless.
It can be difficult to tell what a lump is just by feeling it, but if your GP suspects that you might have a cancer they will refer you to the appropriate specialist for further tests.
2. Coughing, breathlessness and hoarseness
There are many medical conditions that can cause 'chesty' symptoms like coughing and breathlessness (for example, infections and inflammations), but in some cases these symptoms may be a sign of lung cancer. If you have a cough or feel breathless for more than two weeks you should see your GP. You should also tell your GP if you have any blood in your sputum (phlegm) when you cough.
Laryngitis (inflammation of the larynx) is common and can cause a hoarse voice. In a small number of people, a hoarse voice may be a sign of cancer of the larynx (voice box). If hoarseness continues for longer than two weeks, you should tell your GP.
3. Changes in bowel habit
Symptoms of bowel cancer may include blood in your stools (bowel motion). The blood would usually be dark but can be bright red in colour. Fresh, bright red blood is usually a sign of piles (haemorrhoids).
You may notice a change in your normal bowel pattern (such as diarrhoea or constipation) for no obvious reason. You might have a feeling of not having emptied your bowel properly after a bowel motion. Some people also notice that they have pain in the abdomen or back passage.
Remember that altered bowel habits aren't always caused by cancer, but can be caused by changes in diet, some medicines, anxiety, and other medical conditions.
4. Bleeding
Any unexplained bleeding is a sign that there is something wrong and should always be checked out by your GP.
As previously mentioned, bleeding from the back passage is most commonly caused by piles, but can sometimes be due to cancer of the bowel or rectum.
Cancer of the womb or cervix can cause women to bleed between periods or after sex. Women who have any vaginal bleeding after they have had their menopause should see their GP. If necessary your GP will refer you to a gynaecologist.
Blood in your urine may be caused by bladder or kidney cancer. It can also be caused by infection. If you notice blood in your urine it is important to see your GP for a check-up. (It may be helpful to know that the colouring in some medicines or food can cause urine to look pink, as can natural foods, such as beetroot.)
Coughing up blood in your sputum may be caused by serious chest infections, but can sometimes be a sign of lung cancer.
Vomiting blood can be a sign of stomach cancer, although it can also be due to a stomach ulcer. Therefore, it is important to have this checked out by your GP.
Bruising and nosebleeds are rarely signs of cancer, but can in some cases be caused by leukaemia. However, people with leukaemia often have other troublesome symptoms too.
5. Moles
Malignant melanoma is a type of skin cancer that often starts with a change in the appearance of normal skin. This can look like an abnormal new mole. Less than a third of melanomas develop in existing moles. It can be difficult to tell the difference between a mole and a melanoma, but any of the following changes should be checked out:
Asymmetry Moles are usually regular and symmetrical in shape. Melanomas are likely to be irregular or asymmetrical.
Border Moles usually have a well-defined regular border. Melanomas are more likely to have an irregular border with jagged edges.
Colour Moles tend to be a single brown. Melanomas often have more than one colour. They may be varying shades of brown mixed with black, red, pink, white or a bluish tint.
Size Moles are normally no bigger than the blunt end of a pencil (about 6mm (½ inch) across). Melanomas are usually more than 7mm (½ inch) in diameter.
Itching, crusting or bleeding may also occur in melanomas – these are less common signs but should not be ignored.
6. Unexplained weight loss
If you have lost a lot of weight over a short period of time (a couple of months), that cannot be explained by changes in your diet, increased exercise or stress, it is important to tell your GP. Other symptoms, such as sickness, pain and fatigue also tend to occur when a person experiences weight loss due to cancer.
If your GP suspects that you may have cancer, an urgent referral will be made to a specialist. There are guidelines produced by the National Institute for Health and Clinical Excellence (NICE) to help GPs identify when symptoms could be due to cancer or some other condition. An urgent referral usually means that the specialist will see you within two weeks. The specialist can carry out other investigations, such as a biopsy or various scans, to find the cause of your symptoms and plan any treatment necessary.
If your GP thinks your symptoms are not caused by cancer they may still refer you to a specialist for advice, but the referral is likely to be non-urgent and it will take longer for you to be seen.
Remember – in most cases, your symptoms will turn out to be caused by something other than cancer, but they can still be signs of illness and so you won't be wasting your doctor's time by getting them checked out.
1. Sarcomas
Sarcomas are very rare. They are a group of cancers that form in the connective or supportive tissues of the body such as muscle, bone and fatty tissue. They account for less than 1% (1 in 100) of cancers.
Sarcomas are split into two main types:
a. bone sarcomas - that are found in the bones
b. soft tissue sarcomas - that develop in the other supportive tissues of the body.
2. Carcinomas
The majority of cancers, about 85% (85 in a 100), are carcinomas. They start in the epithelium, which is the covering (or lining) of organs and of the body (the skin). The common forms of breast, lung, prostate and bowel cancer are all carcinomas.
Carcinomas are named after the type of epithelial cell that they started in and the part of the body that is affected. There are four different types of epithelial cells:
a. squamous cells - that line different parts of the body, such as the mouth, gullet (oesophagus), and the airways
b. adeno cells - form the lining of all the glands in the body and can be found in organs such as the stomach, ovaries, kidneys and prostate
c. transitional cells - are only found in the lining of the bladder and parts of the urinary system
d. basal cells - that are found in one of the layers of the skin.
A cancer that starts in squamous cells is called a squamous cell carcinoma. A cancer that starts in glandular cells is called an adenocarcinoma. Cancers that start in transitional cells are transitional cell carcinomas, and those that start in basal cells are basal cell carcinomas.
3. Leukaemias and lymphomas
These occur in the tissues where white blood cells (which fight infection in the body) are formed, i.e. the bone marrow and lymphatic system. Leukaemia and lymphoma are quite rare and make up about 6.5% (6.5 in 100) of all cancers.
4. Others forms of cancer
Brain tumours and other very rare forms of cancer make up the remainder of cancers.
The organs and tissues of the body are made up of tiny building blocks called cells. Cancer is a disease of these cells.
Cells in different parts of the body may look and work differently but most reproduce themselves in the same way. Cells are constantly becoming old and dying, and new cells are produced to replace them. Normally, cells divide in an orderly and controlled manner. If for some reason the process gets out of control, the cells carry on dividing, developing into a lump which is called a tumour.
Tumours can be either benign or malignant. Cancer is the name given to a malignant tumour. Doctors can tell if a tumour is benign or malignant by examining a small sample of cells under a microscope. This is called a biopsy.In a benign tumour the cells do not spread to other parts of the body and so are not cancerous. However, if they continue to grow at the original site, they may cause a problem by pressing on the surrounding organs.
A malignant tumour consists of cancer cells that have the ability to spread beyond the original area. If the tumour is left untreated, it may spread into and destroy surrounding tissue. Sometimes cells break away from the original (primary) cancer. They may spread to other organs in the body through the bloodstream or lymphatic system.
The lymphatic system is part of the immune system - the body's natural defence against infection and disease. It is a complex system made up of organs, such as bone marrow, the thymus, the spleen, and lymph nodes. The lymph nodes (or glands) throughout the body are connected by a network of tiny lymphatic ducts.
When the cancer cells reach a new area they may go on dividing and form a new tumour. This is known as a secondary cancer or metastasis.
It is important to realise that cancer is not a single disease with a single type of treatment. There are more than 200 different kinds of cancer, each with its own name and treatment.